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Cashew is Healthy for the Entire Family



                 Brazil and Cashew Nuts Intake Improve Body

                 Composition and Endothelial Health in Women at


                 Cardiometabolic Risk (Brazilian Nuts Study):

                 A Randomised Controlled Trial

                                                                                      Cashew and Women’s Health







                 Published online by Cambridge University Press:  23 February 2022


                 Author(s): Ana Paula Silva Caldas , Daniela Mayumi Usuda Prado Rocha ,
                 Helen Hermana Miranda Hermsdorff , Josefina Bressan,    Ana Paula Dionísio


                 Author Affiliation
                 •   Department of Nutrition and Health, Universidade Federal de Viçosa,
                     Viçosa, Minas Gerais, 36570-900, Brazil.
                 •   Embrapa Agroindústria Tropical, Sara Mesquita Street, 2270, 60511-110,
                     Fortaleza, Ceará, Brazil.


                 Abstract
                 Several mechanisms have been proposed for the beneficial effect of nuts on health. However, Brazil and cashew nuts
                 remain the least studied. We aim to evaluate the effect of these nuts within an energy-restricted diet on body weight,
                 body composition, cardiometabolic markers and endothelial function in cardiometabolic risk women. Brazilian nuts
                 study is a randomised controlled parallel 8-week dietary intervention trial. Forty women were randomly allocated to (1)
                 control group: energy-restricted diet without nuts, n 19 or (2) Brazil and cashew nuts group (BN-Group): energy-re-
                 stricted diet containing daily 45 g of nuts (15 g of Brazil nuts + 30 g of cashew nuts), n 21. At the beginning and final in-
                 tervention, anthropometry, body composition and blood pressure were measured. Fasting blood sampling was obtained
                 to evaluate lipid profile, glucose homeostasis and endothelial function markers.


                 Results: After 8-week, plasma Se concentration increased in BN-group (Δ = + 31·5 (SEM 7·8) μg/l; P = 0·001). Brazil
                 and cashew nuts intake reduced total body fat (–1·3 (SEM 0·4) %) parallel to improvement of lean mass percentage in
                 BN-group compared with the control. Besides, the soluble adhesion molecule VCAM-1 decreased (24·03 (SEM 15·7)
                 pg/ml v. -22·2 (SEM 10·3) pg/ml; P = 0·019) after Brazil and cashew nuts intake compared with the control. However,
                 lipid and glucose profile markers, apolipoproteins and blood pressure remained unchanged after the intervention.


                 Conclusion: Thus, the addition of Brazil and cashew nuts to an energy-restricted diet can be a healthy strategy to
                 improve body composition, Se status and endothelial inflammation in cardiometabolic risk women.


                 Keywords: Brazil nut; VCAM-1; body fat; cashew nut; obesity; weight loss.















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