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Cashew is Healthy for the Entire Family



                 Consumption of Cashew Nuts Does not Influence Blood

                 Lipids or other Markers of Cardiovascular Disease in


                 Humans: A Randomized Controlled Trial




                                                                                            Cashew and Lipids




                 Author(s): Baer David J, Novotny Janet A

                 Journal article: The American Journal of Clinical Nutrition
                 Volume 109, Issue 2, February 2019, Pages 269-275


                 Background
                 The US Food and Drug Administration (FDA) approved a qualified health
                 claim for tree nuts and reduction of cardiovascular disease. However, ca-
                 shews are excluded from that claim due to their content of saturated fats,
                 which is predominantly stearic acid. Because stearic acid is neutral with
                 respect to blood lipids, several studies have been conducted to test the effect
                 of cashew nuts on blood lipids, and these studies have produced conflicting   Results: There were no signifi-
                 results.
                                                                                      cant differences in blood lipids,
                                                                                      blood pressure, augmentation
                 Objectives                                                           index, blood glucose, endothelin,
                 The aim of this study was to conduct a highly controlled intervention to deter-  adhesion molecules, or clotting
                 mine the effect of cashews fed at the amount specified in the health claim on   factors in this weight-stable
                 risk factors for cardiovascular disease.
                                                                                      cohort. PCSK9 was significantly
                                                                                      decreased after cashew con-
                 Methods                                                              sumption, although there was no
                 A total of 42 adults participated in a controlled-feeding study conducted as a   change in LDL cholesterol.
                 randomized crossover trial with 2 treatment phases. The volunteers were pro-
                 vided the same base diet in both treatment phases, with no additions during
                 the control phase and with the addition of 1.5 servings (42 g) of cashews/d   Conclusion
                 for the cashew nut phase. During the cashew nut phase, the amount of all   Consumption of 1.5 servings of
                 foods was decreased proportionally to achieve isocaloric overall diets in the   cashew nuts/d, the amount associ-
                 2 phases. After 4 week of intervention, assessments included blood lipids,   ated with the FDA qualified health
                 blood pressure, central (aortic) pressure, augmentation index, blood glucose,   claim for tree nuts and cardiovascular
                 endothelin, proprotein convertase subtilisin/kexin type 9 (PCSK9), adhesion   disease, did not positively or adversely
                 molecules, and clotting and inflammatory factors.                    affect any of the primary risk factors
                                                                                      for cardiovascular disease. This trial
                                                                                      was registered at clinicaltrials.gov as
                                                                                      NCT02628171.















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